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Step into Syeni Salon & Spa, where old world Mediterranean style and the antiquity of the Tobacco & Mule Exchange come together. Located in the Downtown Historic Apex. The exposed beams, ceilings, and wooden floors take you to times past. The furnishings and features blend historic and modern into a very inviting atmosphere. Syeni’s relaxation room is decorated with beaded and embroidered fabrics from Turkey that make it a welcoming retreat.

Our salon staff is highly trained and can offer you some of the highest quality services available in the area. We are proud to use the highly regarded and world reknowned line of Redken Hair Color and Styling products.

All of the traditional services are offered for men and women, but with an added Twist, which makes this Salon & Spa so unique.

Our pedicure room is lavishly designed with custom tile work and glass whirlpool bowls, quite a beautiful setting for revitalizing tired feet.

Pure relaxation awaits you at Syeni Salon & Spa. Come and experience the old world charm blended with local hometown history – Downtown Historic Apex, North Carolina.

Contact Us Using the Form Below

If you have any questions, comments or concerns.

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To Ensure an incredible Experience
Please arrive 15 minutes before your scheduled appointment time. Unfortunately, late arrivals will not receive an extension on treatments and will be responsible for full service fees. Our scheduling times reflect actual treatment times. Earlier or later appointments can be accommodated but must be booked in advance. No smoking is permitted in our spa environment. We cannot be responsible for valuables and suggest that you refrain from bringing them to the spa. Out of consideration for our other guests, please mute pagers and cell phones in the spa. All prices subject to change. Please note that quoted prices do not include gratuities.
Cancellation and Booking
Cancelling an appointment with 24 hours notice will not result in any charges.We reserve the right to charge 50% of the total scheduled services for a same day cancellation of an appointment unless we are able to fill the appointment time. We reserve the right to charge up to 50% of the scheduled services that are a “no call, no show” appointment. Discounts may be available for groups of 5 or more people. 18% gratuity will be added to all groups with 5 or more people.


(919) 387-4166



225 N. Salem St. Suite 101
Tobacco & Mule Exchange
Apex, NC 27502


Sun & Mon Closed
Tues-Wed 9a–8p
Thur 9a–7p

Fri 9a-6:30

Sat 9a-6p


Please remember that your appointment time is reserved especially for you. This policy has been put in place because both your time and our time are valuable. By giving us 24 hours’ notice, we can reschedule your appointment and possibly free up your original time for another client.

Thank you for your understanding! Effective October 1st, 2013 we are enacting a new policy which will require a credit card number on file to reserve your appointment. This credit card number will be securely stored in our system and will not be charged except per our cancellation policy.